New Research on Pesticide Exposure Risk

A new study, partially funded by APDA, has found that exposure to a common pesticide can leave long-term changes...see more in the brain’s genetic landscape, possibly increasing the risk of Parkinson’s disease (PD). The research, published in Nature’s npj Parkinson’s Disease journal in July 2025, shows that the pesticide rotenone triggers lasting alterations in brain gene […]

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A New Blood Test Could Identify Parkinson’s Disease Before Symptoms Appear

An exciting development is underway as a new RNA-based blood test could help diagnose Parkinson’s disease (PD) prior to...see more the development of motor symptoms. The work, published in Nature Aging, demonstrated a way to target and detect specific sequences contained within transfer RNA (tRNA) for early diagnosis in a simple blood test. This approach will […]

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Joining forces to push for federal research funding

Today in an exciting collaborative effort, three major Parkinson’s disease (PD) advocacy organizations have joined forces to issue a...see more public statement imploring lawmakers to robustly fund the National Institutes of Health (NIH) in the upcoming federal budget in order to keep Parkinson’s disease (PD) research moving forward as quickly as possible. This important joint statement […]

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FDA Approves New Adaptive DBS System

In exciting news, the FDA approved Medtronic’s deep brain stimulation (DBS) system known...see more as BrainSense™. Unlike standard DBS, which delivers electricity to the brain at pre-programmed settings, this technology can sense the brain’s electric signals, known as local field potentials or LFPs, and adjust the stimulation accordingly. This capability, […]

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ONAPGO: A Newly-Approved Medication for OFF Periods in Parkinson’s

ONAPGOTM: A Newly-Approved Medication for OFF Periods in Parkinson’s Breaking News! The first subcutaneous (under the skin) apomorphine infusion,...see more now called ONAPGOTM, was approved by the Food and Drug Administration (FDA) on February 4, 2025. Apomorphine is a dopamine agonist whose effects have a rapid onset. It has been available in the US as a […]

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EPA Bans TCE, a Solvent Linked to PD

In an exciting development for the Parkinson’s disease (PD) community, the Environmental Protection Agency (EPA) banned two solvents, trichloroethylene...see more (TCE) and perchloroethylene, that are found in many common industry and household products such as cleaners, lubricants, and glue. Both have been found to contribute to the increased risk of various cancers and other health conditions. […]

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Adaptive DBS – a new approach to improve PD symptoms

Deep brain stimulation (DBS) is a surgical procedure in which thin electrodes are implanted into parts of the brain...see more to alter brain circuitry. It is used in the treatment of several neurologic conditions including Parkinson’s disease (PD), in which the electricity disrupts abnormal brain signals that allows the brain to restore more normal movement. Currently, […]

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Recently published research on induced pluripotent stem cells by APDA-funded researchers

APDA-funded researchers at Brigham and Women’s Hospital, including Drs. Isabel Lam and Anastasia Kuzkina, under the leadership of Dr. ...see more Vikram Khurana, the Director of APDA’s Center for Advanced Research at Brigham and Women’s Hospital, recently published a paper demonstrating a novel technology that more rapidly turns stem cells created from the cells of an adult […]

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